Abstract Background Acro-osteolysis (AO) refers to resorption of the distal finger and toe phalanges.It displays two patterns: (i) diffuse AO and (ii) transverse or bandlike AO.AO can be a sign of local distress (e.g.of toxic origin), but is very often a sign of a constitutional or systemic acquired disorder.Case presentation A 15-year-old girl was
The MARCH family of RING-finger E3 ubiquitin ligases comprise 11 members that have 3 piece horse wall art been reported to play a variety of roles in the downregulation of cell-surface proteins involved in adaptive immunity.The RING-CH domain of MARCH proteins is thought to ubiquitinate the cytoplasmic tails (CTs) of target proteins, leading to pro
The Roman bridge near Canosa di Puglia (Southern Italy) currently has a very different morphology from the one planned by its builders in the second century AD as part of the program for the construction of the Via Traiana.Although the piers, the abutments and the foundation platea are still preserved from the Roman age, the changes made over the c
Magic and dining have long been popular forms of entertainment.What is more, both involve some kind of transformation, and yet while the more theatrical aspects of dining have grown in popularity in recent decades, there is a surprising paucity of magical food and beverage experiences out there.In rike knife lamella this article, we trace the histo